个人情况:
李德富,工学博士,教授,硕士生导师
通讯地址:四川大学化学工程学院
邮编:610065
邮箱:
教育和工作经历:
1998/09-2001/07,山东省临沂市第一中学,高中
2001/09-2005/07,四川大学,化学工程学院制药与生物工程系,大学本科/学士学位
2005/09-2010/07,四川大学,化学工程学院制药与生物工程系,硕博连读研究生/博士学位
2010/07-2014/06,四川大学,化学工程学院制药与生物工程系,讲师
2013/12-至今四川大学,化学工程学院生物化工专业,硕士生导师
2014/07-至今 四川大学,化学工程学院制药与生物工程系,副教授
社会工作:
2012/08-2013/07,江苏省委组织部“科技镇长团”成员,江苏省镇江市丹徒区宜城街道党工委,副书记
科学研究
研究方向:
天然高分子的化学改性;生物质化学与材料
承担科研项目:
1.纳米粘土改性胶原蛋白塑料的结构与性能.四川大学青年教师科研启动基金,2011.1-2012.12,项目负责人;
2. brookfield粘度计功能的深度开发及在大学生创新实验中的应用.四川大学实验技术立项项目,2011.11-2012.11,项目负责人;
3.生物工程专业课程探究式教学方式的改革与实践.四川省“高等教育质量工程”建设项目,2012-2015,负责人;
4.纳米粘土在胶原蛋白塑料中的剥离行为及诱导作用研究.国家自然科学基金青年基金,2013.1-2015.12,项目负责人;
5.活性有机蒙脱土在胶原蛋白中的剥离行为及诱导作用研究.高等学校博士学科点专项科研基金,2013.1-2015.12,项目负责人;
6.一种功能性明胶粉条及其制备方法,企业委托,2014.4-2019.4,项目负责人;
7.醛多糖改性胶原蛋白塑料的微相分离行为研究.四川大学优秀青年学者科研基金,2015.1-2017.12,项目负责人;
8. 2016年度“化工之星”优秀青年人才培养计划,项目负责人;
9.异构双层自愈合胶原基骨缺损屏障膜的构筑及性能研究.四川省国际科技创新合作/港澳台科技创新合作项目. 2019.01-30-2020.12,项目负责人。
获奖及发明专利
获奖:
1. 2012年度四川大学教学成果奖二等奖,2017年度四川大学教学成果奖二等奖;
2.四川大学2011届、2013届、2014届、2016届、2017届本科优秀毕业论文指导教师;
3. 2013年度、2018年度四川大学课堂教学质量优秀奖;
4. 2014年度四川大学青年骨干教师奖;
5. 2014-2015学年四川大学学术型社团优秀指导教师二等奖,2015-2016学年学术型社团优秀指导教师优秀奖;
6. 2015中国化工学会年会优秀论文奖;
7.四川大学化学工程学院2016年优秀共产党员,四川大学化学工程学院2018年优秀党务工作者;
8.四川大学2017年、2018年大学生创新创业教育优秀指导教师;
9. 2019年第五届中国“互联网 ”大学生创新创业大赛银奖指导教师;
10. 2019年四川省第五届“互联网 ”学生创新创业大赛金奖指导教师;
11.四川省2019年第五届“互联网 ”学生创新创业大赛优秀创新创业导师奖;
12.四川大学2019年第五届“互联网 ”大学生创新创业大赛一等奖指导教师;
13. 2019年第五届全国大学生制药工程设计竞赛二等奖指导教师等荣誉称号。
第一发明人申请发明专利:
1.一种功能性明胶粉条及其制备方法.中国发明专利,专利号:zl201010119060.7
2.一种纳米复合材料中纳米粘土的冷冻分散方法.中国发明专利,专利号:zl201110130461.7
3.一种酚酸类改性胶原蛋白面膜及其制备方法.中国发明专利,专利号:zl201110309522.6
4.一种ii型胶原和硫酸软骨素的综合提取工艺.中国发明专利,专利号:zl201210196922.5
5.一种废水中阳离子染料吸附剂及其制备方法.中国发明专利,专利号:zl201210482472.6
6.一种明胶基纳米复合材料及其制备方法.中国发明专利,专利号:zl201210528098.9
7.一种功能性明胶食品包装膜及其制备方法.中国发明专利,专利号:zl201510137884.x
8.一种纳米复合大豆蛋白塑料及其制备方法.中国发明专利,专利号:zl201510304629.x
9.一种纳米银复合胶原医用敷料及其制备方法.中国发明专利,专利号:zl201710115523.4
10.一种孔道结构可控的明胶细胞支架及其制备方法.中国发明专利,申请号:201810001229.5
发表论文
42.lei deng, xinying li, keyan miao, xinyan mao, miao han,defu li, changdao mu, liming ge*. development ofdisulfide bondcrosslinkedgelatin/ε-polylysine active edible film with antibacterial and antioxidant activities.food and bioprocess technology,2020,13, 577–588
41.xi zhao, xinying li, xiaofen xie, jinfeng lei, liming ge,* lun yuan,defu li,*changdao mu. controlling the pore structure of collagen sponge by adjusting the crosslinking degree for construction of heterogeneous double-layer bone barrier membrane.acs applied bio materials, 2020,2020, 3, 2058−2067
40. yongbin xu, yaxin zi, jinfeng lei, xingyue mo, zilun shao, yuyao wu, ye tian,*defu li,* changdao mu. ph-responsive nanoparticles based on cholesterol/imidazole modified oxidized-starch for targeted anticancer drug delivery.carbohydrate polymers, 2020, 233, 115858
39. yongbo lyu, mengchao yu, qisong liu, qingmei zhang, zhanhong liu, ye tian*,defu li*, changdao mu. synthesis of silver nanoparticles using oxidized 1 amylose and combination with curcumin for enhanced antibacterial activity.carbohydrate polymers, 2020, 230, 115573
38. mingjin zhu, xinying li,*, liming ge, yaxin zi, man qi, yulin li,defu li*, changdao mu. green synthesis of κ-carrageenan@ag submicron-particles with high aqueous stability, robust antibacterial activity and low cytotoxicity.materials science & engineering c, 2020, 106, 110185-110194
37. xinyan mao, xinying li,wenjie zhang,lun yuan,lei deng,liming ge, changdao mu, anddefu li*. development of microspheres based on thiol-modified sodium alginate for intestinal-targeted drug delivery.acs applied bio materials, 2019, 2, 5810−5818
36. jinfeng lei, xinying li, shen wang, lun yuan, liming ge,defu li*, changdao mu. facile fabrication of biocompatible gelatin-based self-healing hydrogel.acs applied polymer materials, 2019, 1, 1350−1358
35.韩淼,李德荣,袁柳青,吕永博,葛黎明,李德富,穆畅道.双醛淀粉还原制备纳米银及其在胶原基抗菌敷料中的应用.高分子学报, 2019, 50(4), 366-374
34. lun yuan, xinying li, liming ge, xiaoqi jia,jinfeng lei, changdao mu, anddefu li*. emulsion template method for the fabrication of gelatin-based scaffold with a controllable pore structure.acs applied materials & interfaces, 2019, 11, 269−277.
33. jinfeng lei, meizhou zhang, shen wang, lei deng,defu li*, and changdao mu*.one-pot approach for the synthesis of water-soluble anatase tio2nanoparticle cluster with efficient visible light photocatalytic activity.the journal of physical chemistry c,2018,122(46), 26447–26453.
32. jinfeng lei, lei deng, xinying li, yongbin xu,defu li*, changdao mu*. comparative study of the physicochemical and photocatalytic properties of water-soluble polymer-capped tio2nanoparticles.environmental science and pollution research, 2018, 25, 26259–26266.
31.梁伟杰,吕永博,穆畅道,李德富*.高性能正辛酸塑化明胶膜的热压法制备与表征.皮革科学与工程, 2018, 28(3), 11-19.
30. liming ge, yongbin xu, xinying li, lun yuan, huan tan,defu li*,changdao mu. fabrication of antibacterial collagen-based composite wound dressing.acs sustainable chemistry and engineering.2018,6(7), 9153–9166.
29. he ren, yongbo lyu, xinying li, shuxiao zhang, yusong ye,defu li*, changdao mu*.preparation and characterization of dialdehyde β-cyclodextrin with broad-spectrum antibacterial activity.food research international, 2018, 111, 237-243.
28. liming ge, mingjin zhu, xinying li, yongbin xu*, xiaonan ma, rong shi,defu li*, changdao mu. development of active rosmarinic acid-gelatin biodegradable films with antioxidant and long-term antibacterial activities.food hydrocolloids, 2018, 83, 308-316.
27. yaxin zi, mingjin zhu, xinying li, yongbin xu, hao wei,defu li*,changdao mu*. effects of carboxyl and aldehyde groups on the antibacterial activity of oxidized amylose.carbohydrate polymers192 (2018) 118-125.
26.訾娅鑫,雷金凤,徐志朗,李德富*,穆畅道*.多糖的氧化改性及在生物医药领域的应用.生物加工过程, 2018, 16(1): 31-37 (优秀生物化工青年学者专刊)
25. youxin ye, he ren, shu zhu, huan tan, xinying li*,defu li*, changdao mu. synthesis of oxidized β-cyclodextrin with high aqueous solubility and broad-spectrum antimicrobial activity.carbohydrate polymers, 2017, 177: 97-104.
24. yongbo lyu, he ren, mengchao yu, xinying li,defu li*, changdao mu*.using oxidized amylose as carrier of linalool for the development of antibacterial wound dressing.carbohydrate polymers, 2017, 174, 1095–1105
23. mingjin zhu, liming ge, yongbo lyu, yaxin zi, xinying li*,defu li*, changdao mu.preparation, characterization and antibacterial activity of oxidizedκ-carrageenan.carbohydrate polymers, 2017, 174, 1051–1058.
22.youxin ye, mingjin zhu, keyan miao, xinying li*,defu li*, changdao mu.development of antimicrobial gelatin-based edible films by incorporation oftrans-anethole/β-cyclodextrin inclusion complex.food and bioprocess technology,2017, 10(10): 1844–1853.
21. liming ge, mingjin zhu, yongbin xu, xinying li*,defu li*, changdao mu.development of antimicrobial and controlled biodegradable gelatin-based edible films containing nisin and amino-functionalized montmorillonite.food and bioprocess technology, 2017, 10:1727–1736
20.meizhou zhang, jinfeng lei, yifeng shi, lina zhang, youxin ye,defu li*, changdao mu*. molecular weight effects of peg on the crystal structure and photocatalytic activities of peg-capped tio2nanoparticles.rsc advances, 2016, 6, 83366 - 83372
19. ying zhou, youxin ye, wenwen zhang, songling li, jing chen, shiting wang,defu li*, changdao mu*. oxidized amylose with high carboxyl content: a promising solubilizer and carrier of linalool for antimicrobial activity.carbohydrate polymers, 2016, 154, 13-19.
18. liming ge, yongbin xu, weijie liang, xinying li*,defu li*, changdao mu. short-range and long-range cross-linking effects of polygenipin on gelatin-based composite materials.journal of biomedical materials research: part a, 2016, 104a: 2712–2722.
17.defu li*, youxin ye, derong li, xinying li, changdao mu*. biological properties of dialdehyde carboxymethyl cellulose crosslinked gelatin-peg composite hydrogel fibers for wound dressings.carbohydrate polymers, 2016, 137, 508-514.
16. ying zhou, xinying li, yongbo lv, yifeng shi, yu zeng,defu li*, changdao mu*. effect of oxidation level on the inclusion capacity and solution stability of oxidized amylose in aqueous solution.carbohydrate polymers,2016, 138, 41-48.
15. liming ge, xinying li, run zhang, tianhan yang, xiaowei ye,defu li*, changdao mu.development and characterisation of dialdehyde xanthan gum crosslinked gelatin based edible films incorporated with amino-functionalized montmorillonite.food hydrocolloids, 2015, 51, 129-135.
14. wenwen zhang, xinying li, taocheng yu, lun yuan, gang rao,defu li*, changdao mu*. physicochemical and release characterisation of the inclusion complex of β-cyclodextrin andtrans-anethole.food research international, 2015, 74, 55-62.
13. kechen li, jiangen peng, meizhou zhang, jian heng,defu li*, changdao mu*. comparative study of the effects of anatase and rutile titanium dioxide nanoparticles on the structure and properties of waterborne polyurethane.colloids and surfaces a: physicochemical and engineering aspects,2015, 470, 92-99.
12. jimin guo, liming ge, xinying li, changdao mu,defu li*. periodate oxidation of xanthan gum and its crosslinking effects on gelatin-based edible films.food hydrocolloids, 2014, 39, 243-250.
11. xinying li, hongyan ma, huilian huang,defu li, shun yao. natural anthocyanins form phytoresources and their chemical researcher.natural productresearch, 2013, 27(4-5): 456-469.
10. changdao mu, ke zhang, wei lin,defu li*.ring-opening polymerization of genipin and its long-range crosslinking effect on collagen hydrogel.journal of biomedical materials research: part a, 2013, 101a, 385-393.
9. changdao mu, xinying li, yige zhao, hanguang zhang, liangjie wang,defu li*.freezing/thawing effects on the exfoliation of montmorillonite in gelatin-based bionanocomposite.journal of applied polymer science, 2013, 128, 3141-3148.
8. changdao mu, xinying li, jimin guo, caixia bi,defu li*. effects of montmorillonite on the structure and properties of gelatin-peg composite fibers.journal of applied polymer science, 2013, 129, 773-778.
7. jimin guo, xinying li, changdao mu, hanguang zhang, pan qin,defu li*. freezing-thawing effects on the properties of dialdehyde carboxymethyl cellulose crosslinked gelatin-mmt composite films.food hydrocolloids, 2013, 33, 273-279.
6. changdao mu, jimin guo, xinying li, wei lin,defu li*.preparation and properties of dialdehyde carboxymethyl cellulose crosslinked gelatin edible films.food hydrocolloids, 2012, 27, 22-29. (esi top 1%高引用率论文)
5. lirong he, changdao mu,defu li, wei lin.revisit the pre-transition of type i collagen denaturation in dilute solution by ultrasensitive differential scanning calorimetry.thermochimica acta, 2012, 548, 1-5.
4. dihan su, chunhua wang, sumei cai, changdao mu,defu li, wei lin.influence of palygorskite on the structure and thermal stability of collagen.applied clay science, 2012, 62-63, 41-46.
3.defu li, changdao mu, qian zhang, yuling zhou, wei lin*. effects of microwave irradiation on collagen denaturation.journal of food biochemistry, 2010, 34, 1319-1331.
2.defu li, changdao mu, cai sumei, wei lin. ultrasonicirradiation in the enzymatic extraction of collagen.ultrasonics sonochemistry, 2009, 16, 605-609.
1. changdao mu,defu li,wei lin, yanwei ding, and guangzhao zhang. temperature induced denaturation of collagen in acidic solution.biopolymers, 2007, 86(4), 282-287.